His Excellency Sheikh Mohammed Bin Hamad Al-Thani was appointed Minister of Commerce and Industry in October 2021. He was Deputy Governor and Vice-Chairman of the Qatar Central Bank from March 2018 to October 2021.

In April 2018, Sheikh Mohammed was appointed Chairman of the Board of Directors of the Qatar Financial Markets Authority, and later that year, he was appointed Deputy Chairman of the QFC Regulatory Authority until October 2021. He served as Deputy Chairman of the Board of Directors of Qatar Development Bank from 2019 to 2021.

Prior to his March 2018 Qatar Central Bank appointment, Sheikh Mohammed held a range of senior roles there, including Director of the Risk Management Department until 2012. Following that, for five years, he held the role of Secretary of the Personal Representative of His Highness the Amir for follow-up affairs.